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Aims: This study is geared to evaluating honey as an alternative of conventional antibiotics to treat infections caused by the selected diarrhoeagenic bacteria.
Place and duration of Study: Research laboratory of Federal University of Technology Akure (FUTA), Ondo State, Nigeria between December 2017 to May 2018.
Methodology: Honey samples from ten (10) different locations in Nigeria were screened for possible antibacterial activity on both the clinical and typed cultures of the selected diarrhoeagenic bacteria; Escherichia coli, Salmonella typhimurium, Shigella dysenteriae, Bacillus cereus and Staphylococcus aureus using agar well diffusion method. Conventional antibiotics were used as control. Data obtained were subjected to one way analysis of variance (ANOVA) using XL-Start, 2016 version.
Results: All the honey samples used exerted growth inhibitory activity on all the test bacteria including the ones that were resistant to the conventional antibiotics (Ofloxacin and augmentin) used as control. In some cases, the growth inhibitions mediated by the honey samples were superior to that of the conventional antibiotics.
Conclusion: This study showed that honey has antibacterial activity against the selected bacteria and therefore can be exploited as an alternative to conventional antibiotics to treat infections caused by the selected diarrhoeagenic bacteria especially the ones that were resistant to conventional antibiotics.