Prevalence of Mycobacterium tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State, Nigeria
Odiase, Edgar Onyeka *
Department of Medical Laboratory Science, Igbinedion University, Okada Edo State, Nigeria.
Olley Mitsan
Department of Medical Laboratory Science, Igbinedion University, Okada Edo State, Nigeria.
Daniel Ohilebo Ugbomoiko
Department of Medical Laboratory Science, Igbinedion University, Okada Edo State, Nigeria.
Theophilus Ogie Erameh
Department of Medical Laboratory Science, Igbinedion University, Okada Edo State, Nigeria.
Ezekiel Dauda Gambo
Department of Medical Laboratory Science, Igbinedion University, Okada Edo State, Nigeria.
Ofili Sandra Kanwulia
Federal Medical Center Asaba, Delta State, Nigeria.
Muhammad Adamu Ibrahim
Department of Immunology, School of Medical Laboratory Science, Usmanu Danfodiyo University, Sokoto, Nigeria.
Paul Yiran Ntasin
Department of Immunology, School of Medical Laboratory Science, Usmanu Danfodiyo University, Sokoto, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Aim: The study aimed to ascertain the prevalence of tuberculosis among HIV-positive patients at the Federal Medical Center Asaba in Delta State, Nigeria.
Study Design: This study engaged a cross-sectional study design to prevalence of Mycobacterium Tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State.
Place and Duration of the Study: The study was conducted in Federal Medical Center. Data collection spanned a specific duration from November, 2022 to January, 2023.
Methodology: A total of 188 samples were obtained from known HIV patients. The patients were selected by random sampling technique. The samples were analysed using GeneXpert machine (GX2.1 model) with the nuclei acid amplification (NAA) of DNA mycobacterium tuberculosis complex (MTBC) and resistance to rifampicin. Demographic data of participants were obtained through questionnaires.
Results: Out of 188 samples from HIV patients analyzed, MTB was detected in 13 (8.7%) patients with the highest prevalence recorded among male subjects 6(12%). Age group 19-29 was the most prevalent of MTB among the test subjects.
Conclusion: Mycobacterium tuberculosis is widespread among HIV patients in Asaba, Delta state, according to these data. As a result, patients must be encouraged to adhere to treatment and preventive measures.
Keywords: Human immunodeficiency virus, Mycobacteruim tuberculosis, GeneXpert, asaba